Özet:
Background: Hydatid cyst secretes numerous immunomodulatory molecules
to the host, and the host reacts these molecules
by activating immune response. It is also known
that, immune cells generally produce more oxidative products.
Aim: In this study, we aimed to evaluate the
antioxidant enzyme using catalase (CAT) and oxidant enzyme using lipid hydroperoxide (LOOH)
levels in the serum samples before and after the
surgical interventions in patients with pulmonary cystic echinococcus (CE).
Patients and Methods: Forty patients with pulmonary CE who underwent surgery and 40 healthy
individuals were enrolled to the study. Patients
were divided in two groups; group 1 (n=40) consisted of patients with pulmonary CE, and group 2
(n=40) consisted of healthy subjects.
Before and after surgical interventions serum
CAT and LOOH levels were measured.
Results: Compared to group 2, group 1 had
significantly lower CAT and higher LOOH levels
before surgery (both p < 0.001). In group 1; CAT
levels were significantly increased and LOOH
levels significantly increased after the surgical
intervention (both p < 0.001).
Conclusions: The present study showed that
oxidative stress increased in patients with pulmonary CE, may be consequence of immune response of the host, and these levels decreased
after the surgical intervention.
